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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
23.94
Human Site:
Y617
Identified Species:
47.88
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
Y617
W
R
P
R
F
R
Y
Y
H
W
T
L
S
F
L
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
C661
Y
L
F
V
N
L
A
C
A
L
Q
T
L
L
R
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
Y594
W
R
P
R
F
R
Y
Y
H
W
T
L
S
F
L
Dog
Lupus familis
XP_543029
1042
114973
Y569
S
M
F
F
L
M
C
Y
M
F
V
N
L
A
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
Y617
W
R
P
R
F
R
Y
Y
H
W
T
L
S
F
L
Rat
Rattus norvegicus
Q63633
1139
126228
Y617
W
R
P
R
F
R
Y
Y
H
W
T
L
S
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
Y631
W
R
P
R
F
K
Y
Y
H
W
T
L
S
F
L
Chicken
Gallus gallus
NP_001006371
1125
125222
Y611
W
R
P
R
F
K
Y
Y
H
W
T
L
S
F
L
Frog
Xenopus laevis
Q0VGW6
899
98326
V426
T
I
A
G
I
V
T
V
F
Y
L
I
A
Y
A
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
I426
Q
L
N
V
I
A
G
I
V
T
V
F
Y
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
T547
L
D
F
F
F
L
M
T
L
S
L
L
G
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
I623
W
G
I
R
N
V
F
I
G
S
G
L
G
G
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
93.3
93.3
0
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
100
13.3
N.A.
100
100
N.A.
100
100
26.6
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
9
0
0
0
9
17
17
% A
% Cys:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
25
17
59
0
9
0
9
9
0
9
0
50
0
% F
% Gly:
0
9
0
9
0
0
9
0
9
0
9
0
17
9
0
% G
% His:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
17
0
0
17
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
17
0
0
9
17
0
0
9
9
17
67
17
17
59
% L
% Met:
0
9
0
0
0
9
9
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
17
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
50
0
59
0
34
0
0
0
0
0
0
0
0
9
% R
% Ser:
9
0
0
0
0
0
0
0
0
17
0
0
50
0
0
% S
% Thr:
9
0
0
0
0
0
9
9
0
9
50
9
0
0
0
% T
% Val:
0
0
0
17
0
17
0
9
9
0
17
0
0
0
0
% V
% Trp:
59
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
50
59
0
9
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _